Mood Crusher: Agave Nectar You might think agave nectar is a great all-natural swap for sugary syrups in your cocktails (after all, it's one of the main ingredients in the classic margarita) but this isn't exactly true. In fact, agave nectar, the stuff that comes from the plant species bearing its name, has extremely high levels of fructose — even more than high-fructose corn syrup — which is not only terrible for you but can quickly lead to a bad mood. "Fructose is not as easily metabolized as glucose and humans were not meant to ingest large doses of it," explains Kristine Arthur, MD, internist at Orange Coast Memorial Medical Center in Fountain Valley, California. "Fructose has to be metabolized almost entirely by the liver and, over time, this causes fatty liver and elevated triglycerides which can eventually lead to advanced liver disease and coronary artery disease."
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