The over-the-counter version of prescription retinoids, pretty much every single dermatologist we've ever talked to names all of these vitamin A derivatives as the number one anti-aging ingredient. "Retinol is a well-established anti-aging powerhouse," says Shah. "Besides improving skin texture and firmness, it also evens out skin tone and reduces the appearance of pores." Oh, and did we mention that it can also treat acne too? While this retinol is the most common OTC option, there are also other versions (retinyl palmitate, retinaldehyde) which deliver similar benefits, though are slightly less potent. Whichever one you choose, keep in mind that it will take your skin some time to get used to this strong stuff, so start by using it every other night for two weeks, then gradually increasing to nightly use.
Multi-tasking for the win. Vitamin C is a powerful antioxidant, neutralizing skin-damaging free radicals caused by UVA/UVB rays and pollution, helping to prevent both skin cancer and aging, explains Carqueville. As if that weren't enough, it also fades dark spots (and prevents new ones from occurring) and stimulates the production of new collagen, says Shah. (FYI, it sometimes appears as "ascorbic acid" on skincare labels.) Fun fact: Eating it also has similar collagen-boosting benefits, so load up on red peppers and citrus fruits.
This derivative of vitamin B3 delivers a laundry list of benefits for your skin. "It helps repair and maintain the skin barrier, has anti-inflammatory and antioxidant properties, reduces hyperpigmentation and wrinkles, and improves elasticity," says Shah. Translation: This one ingredient can address pretty much any and every complexion concern, be it redness and irritation, spots or signs of aging. Talk about an overachiever.
Made up of amino acids, these are the building blocks of protein. Protein (specifically collagen and elastin) are essential for healthy, youthful skin. "This is a great ingredient for anyone concerned with signs of aging, since they promote collagen and elastin synthesis to improve fine lines, wrinkles, elasticity and firmness," explains Shah. Also nice: Unlike other anti-aging ingredients (we're talking about you, retinol), peptides are typically well-tolerated by most skin types and less likely to cause irritating side effects. #Sold.
