For this other common OTC acne-fighter—which works by dissolving oil and sticky skin cells that can clog pores—follow a protocol similar to that of benzoyl peroxide, gradually decreasing the frequency with which you're using it. Keep in mind that it's also not recommended during pregnancy, says Zeichner, but if you're pregnant and breaking out, don't stress. Topical clindamycin and erythromycin are thought to be safe in pregnancy, says Gilbert, and Zeichner adds that glycolic acid is OK, too.
